NyQuil Overdose Symptoms
NyQuil can be used to treat the symptoms of a cold or the flu. Several varieties of the over-the-counter medication are available, each containing different combinations of medicines. A variety of symptoms may occur with a NyQuil overdose, depending on which type was taken and the amount. The severity of symptoms varies depending on the age of the person who took the medicine and how much was consumed. Symptoms usually begin within 30 minutes to 2 hours after ingestion. If taken in improper doses, each formulation of NyQuil can be toxic.
Symptoms Related to Dextromethorphan
Frequent symptoms seen with an overdose of dextromethorphan include:
- nausea
- vomiting
- dizziness
- hallucinations
- agitation
- a sense of being detached from yourself
- loss of coordination similar to what occurs with alcohol intoxication
Blood pressure and heart rate can also increase. Severe overdoses can lead to seizures, coma and even death.
Symptoms Related to Doxylamine and Chlorpheniramine
Several NyQuil products contain either doxylamine or chlorpheniramine, which are antihistamine medications. Products that contain one of these antihistamines include: -- NyQuil Cold and Flu. -- NyQuil D Cold and Flu. -- NyQuil Severe Cold and Flu. -- Alcohol-Free NyQuil Cold and Flu. -- Children’s NyQuil Cold and Cough. -- NyQuil Cough.
The alcohol-free and children's products contain chlorpheniramine. The others contain doxylamine. Some people -- especially children -- become excited or irritable rather than drowsy and have difficulty walking normally. With more severe overdoses, extreme sluggishness or coma, a further increase in body temperature and seizures may occur.
Symptoms Related to Acetaminophen
Acetaminophen is a pain- and fever-relieving medicine found in: -- NyQuil Cold and Flu. -- NyQuil D Cold and Flu. -- NyQuil Severe Cold and Flu. -- Alcohol-Free NyQuil Cold and Flu.
While generally safe in recommended doses, acetaminophen overdoses can cause liver failure and death. Symptoms occur in stages. Initial symptoms of acetaminophen overdose are typically mild in the first 24 hours, including cramping, mild abdominal pain, nausea and vomiting. With high-level overdoses, significant liver damage and more severe symptoms develop 1 to 3 days after ingestion. At this stage, symptoms include more severe pain in the right, upper abdomen and yellowing of the skin and whites of the eyes, known as jaundice. The liver may fail, with uncontrolled bleeding, confusion, and sluggishness or coma. Death may occur.
Other Considerations, Warnings and Precautions
Liquid formulations of NyQuil not labeled alcohol-free contain 10 percent alcohol. Therefore, typical symptoms of alcohol intoxication can occur quickly. These include dizziness, nausea, vomiting, slurred speech and poor coordination. In addition, NyQuil Severe Cold and Flu contains the decongestant phenylephrine, and NyQuil D Cold and Flu contains the decongestant pseudoephedrine. These decongestants can cause high blood pressure and headaches in with low-level overdose, as well as seizures or brain bleeding with high-level overdose.
NyQuil should only be taken as directed and should not be taken with acetaminophen (Tylenol) or any other cold medications. Symptoms of a NyQuil overdose can vary because of the variety of ingredients. If overdose is suspected, seek emergency medical care 1. This is especially important for acetaminophen overdose. An antidote is available, but early treatment is crucial to preventing liver damage.
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- Critical Care Emergency Medicine; David A. Farcy et al.
- Atlas of Pediatric Emergency Medicine, Second Edition; Binita R. Shah et al.
- Goldfrank's Toxicologic Emergencies, Tenth Edition; Robert S. Hoffman et al.
- Psychopharmacology: High Doses of Dextromethorphan, an NMDA Antagonist, Produce Effects Similar to Classic Hallucinogens
- American Family Physician: Prevention, Diagnosis, and Management of Serotonin Syndrome
- Poisoning and Drug Overdose, Sixth Edition; Kent R. Olson et al.
- DailyMed/U.S. National Library of Medicine. Aleve-D Sinus and Headache. Updated November 6, 2019.
- Nezvalová-Henriksen K, Spigset O, Nordeng H. Effects of ibuprofen, diclofenac, naproxen, and piroxicam on the course of pregnancy and pregnancy outcome: a prospective cohort study. BJOG. 2013;120(8):948-59. doi:10.1111/1471-0528.12192
- Daily Med/U.S. National Library of Medicine. Advil Multi-Symptom Cold and Flu. Updated December 7, 2019.
- Brzeczko AW, Leech R, Stark JG. The advent of a new pseudoephedrine product to combat methamphetamine abuse. Am J Drug Alcohol Abuse. 2013;39(5):284-90. doi:10.3109/00952990.2013.821476
- Zhang Y, Mallefet P. Time-to-onset of cold and flu symptom relief: A randomized, double-blind, placebo-controlled pilot study for a multi-symptom combination product. Int J Clin Pharmacol Ther. 2018;56(12):604-11. doi:10.5414/CP203259
- DailyMed/U.S. National Library of Medicine.Vicks NyQuil Cold and Flu. Updated January 23, 2013.
- DailyMed/U.S. National Library of Medicine. Vicks Children NyQuil Cold and Cough Multi-Symptom Relief. Updated July 15, 2019.
- DailyMed/U.S. National Library of Medicine. Vicks DayQuil Multi-Symptom Cold and Flu Relief. Updated July 10, 2019.
- DailyMed/U.S. National Library of Medicine. Vicks DayQuil Severe and Vicks DayQuil Severe Cold and Flu. Updated January 8, 2020.
- DailyMed/U.S. National Library of Medicine. Tylenol Cold Max Night. Updated October 31, 2018.
- Yoon E, Babar A, Choudhary M, Kutner M, Pyrsopoulos N. Acetaminophen-induced hepatotoxicity: A comprehensive update. J Clin Transl Hepatol. 2016;4(2):131-42. doi:10.14218/JCTH.2015.00052
- Gharti K, Thapa P, Budhathoki U, Bhargava A. Formulation and in vitro evaluation of floating tablets of hydroxypropyl methylcellulose and polyethylene oxide using ranitidine hydrochloride as a model drug. J Young Pharm. 2012;4(4):201-8. doi:10.4103/0975-1483.104363
- Flockhart DA. Dietary restrictions and drug interactions with monoamine oxidase inhibitors: an update. J Clin Psychiatry. 2012;73 Suppl 1:17-24. doi:10.4088/JCP.11096su1c.03
- DailyMed/U.S. National Library of Medicine. Theraflu Severe Nighttime Cold and Cough. Updated March 15, 2018.
- DailyMed/U.S. National Library of Medicine. Theraflu Daytime Severe Cold and Cough. Updated October 9, 2018.
- Bittar RP, Aun M, Garro SL, et al. Acetaminophen hypersensitivity: Myth or reality. J Allergy Clin Immunol. 2013 Feb;131(Suppl_2):AB170. doi:10.1016/j.jaci.2012.12.1270
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